Hi 🌸
Thanks for your question! 🙌
Depend O2 Strength Instant Repair is developed as a strengthening nail treatment for natural nails and can be used alone or under regular nail polish. However, it is not intended for use under base or primer layers with gel polish that is cured with UV/LED, as this can affect the adhesion and durability of the gel polish.
We therefore recommend that you apply the gel polish base directly on a cleaned nail, as the system is designed for💅✨
Wishing you a fabulous day ahead 🌷